Sease-modifying antirheumatic prescription drugs. Ann Rheum Dis 2010, sixty nine:964-975. Emery P, Dorner T: Optimising remedy in rheumatoid arthritis: an assessment of prospective biological markers of response. Ann Rheum Dis 2011, 70:2063-2070. Breedveld FC, Han C, Bala M, van der Heijde D, Baker D, Kavanaugh AF, Maini RN, Lipsky PE: Association among baseline radiographic harm and enhancement in physical operate just after therapy of people with rheumatoid arthritis. Ann Rheum Dis 2005, sixty four:52-55. Maradit-Kremers H, Nicola PJ, Crowson CS, Ballman KV, Gabriel SE: Cardiovascular death in rheumatoid arthritis: a population-based study. Arthritis Rheum 2005, fifty two:722-732. Fautrel B, Verstappen SMM, Boonen A: Economic repercussions and possible benefits. Very best Pract Res Clin Rheumatol 2011, 25:607-624. Tsark EC, Wang W, Teng YC, Arkfeld D, Dodge GR, Kovats S: Differential MHC class II-mediated presentation of rheumatoid arthritis autoantigens by human dendritic cells and macrophages. J Immunol 2002, 169:6625-6633. Blass S, Union A, Raymackers J, Schumann F, Ungethum U, Muller-Steinbach S, De Keyser F, Engel JM, Burmester GR: The tension Carbonic Anhydrase one, Human (His) protein BiP is overexpressed and it is a major B and T cell focus on in rheumatoid arthritis. Arthritis Rheum 2001, 44:761-771. Yoo S-A, You S, Yoon H-J, Kim D-H, Kim H-S, Lee K, Ahn JH, Hwang D, Lee AS, Kim K-J, Park Y-J, Cho C-S, Kim W-U: A novel pathogenic function on the ER chaperone GRP78/BiP in rheumatoid arthritis. J PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/20595784 Exp Med 2012, 209:871-886. Hasnain SZ, Lourie R, Das I, Chen ACH, McGuckin MA: The interplay involving endoplasmic reticulum pressure and inflammation. Immunol Cell Biol 2012, ninety:260-270. Anzilotti C, Pratesi F, Tommasi C, Migliorini P: Peptidylarginine deiminase 4 and citrullination in health and disease. Autoimmun Rev 2010, nine:158-160. Leeming DJ, Bay-Jensen AC, Vassiliadis E, Larsen MR, Henriksen K, Karsdal MA: Post-translational modifications of the extracellular matrix are important activities in cancer progression: prospects for biochemical marker advancement. Biomarkers 2011, 16:193-205. Tanikawa C, Espinosa M, Suzuki A, Masuda K, Yamamoto K, Tsuchiya E, Ueda K, Daigo Y, Nakamura Y, Matsuda K: Regulation of histone modification and chromatin framework with the p53 ADI4 pathway. Nat Commun 2012, three:676. Vossenaar ER, Van Venrooij WJ: Citrullinated proteins: sparks which could ignite the fireplace in rheumatoid arthritis. Arthritis Res Ther 2004, 6:107-111. Masson-Bessiere C, Sebbag M, Girbal-Neuhauser E, Nogueira L, Vincent C, Senshu T, Serre G: The main synovial targets of your rheumatoid arthritisspecific antifilaggrin autoantibodies are deiminated kinds in the alphaand beta-chains of fibrin. J Immunol 2001, 166:4177-4184. Sokolove J, Bromberg R, Deane KD, Lahey LJ, Derber LA, Chandra PE, Edison JD, Gilliland WR, Tibshirani RJ, Norris JM, Holers VM, Robinson WH: Autoantibody epitope spreading inside the pre-clinical phase predicts development to rheumatoid arthritis. PLoS A single 2012, seven:e35296. Makrygiannakis D, Hermansson M, Ulfgren A-K, Nicholas AP, Zendman AJW, Eklund A, Grunewald J, Skold CM, Klareskog L, Catrina AI: Cigarette smoking improves peptidylarginine deiminase 2 enzyme expression in human lungs and boosts citrullination in BAL cells. Ann Rheum Dis 2008, sixty seven:1488-1492. Klareskog L, Stolt P, Lundberg K, Kallberg H, Bengtsson C, Grunewald J, Ronnelid J, Harris HE, Ulfgren AK, Rantapaa-Dahlqvist S, Eklund A, Padyukov L, Alfredsson L: A whole new product for an etiology of rheumatoid arthritis: using tobacco may perhaps set off HLA-DR (shared epitope)-restricte.